Growth rates of tiger muskellunge (muskellunge Esox masquinongy ♀ x northern pike E. lucius ♂) fed diets containing 35, 45, or 55% crude protein for 5 weeks at 17, 20, or 23°C were compared. Fish fed diets containing 45 or 55% protein grew faster at all temperatures than those fed 35% protein. Growth of tiger muskellunge fed a diet containing either 45 or 55% protein did not increase significantly at optimum growth temperatures (20 or 23°C). At 17°C, below the optimum temperature range, growth did increase when the percentage of protein in the diet was increased.